AN- OVER REVIEW OF ANTIBIOTICS

Abstract

Antibiotics are the antimicrobial agent or antibacterial agent, they having both bactericidal or bacteriostatic action against microorganism. first antibiotic in 1877 when he observed that certain bacteria release substances that kill other bacteria unknowingly described by louis pasteur. some of the antibiotics like sulfonamide they active against gram positive or gram negative bacterial also. and penicillin and its like derivative etc. we call broad spectrum antibiotic. and they act by alteration of protein synthesis, antimetabolite activity, inhibition of cell wall synthesis and inhibition of nucleic acid synthesis etc. they produce also resistance because of misuse of antibiotics ,anomalous combinations ,enhanced transmission of resistance factors, and the reservoir hypothesis.